Wellbutrin

Yes all very interesting, the mechanisms of WB versus SSRI.

I have been on stims for ADHD for 20 years and I also take Wellbutrin for depression, but it doesn’t do shit for my ADHD if I missed a few days of amph, or cause any appetite suppression or weight loss but for those without a long history of amphetamines, Wellbutrin is more likely to put some pep in your step and also you may lose weight.
I forget which dose is better for depression and which is better for ADHD. But there is also the SR vs ER thing.

A Virgin ADHD brain - one not tainted by years of drug use - may find WB very helpful for focus and all that but one good thing I’ve found is it doesn’t make me gain weight. Unlike the demon Lexapro did and took me 8 months to get my metabolism untucked.

Oh and a virgin brain (or at least not a brain that’s been through the wringer) may also find it to be somewhat euphoric. Or so Ive heard. Ooh to be so lucky to create this Reddit thread: “Does WB make anyone else feel like Superman?”

AnnaSofia said:

Yes all very interesting, the mechanisms of WB versus SSRI.

I have been on stims for ADHD for 20 years and I also take Wellbutrin for depression, but it doesn’t do shit for my ADHD if I missed a few days of amph, or cause any appetite suppression or weight loss but for those without a long history of amphetamines, Wellbutrin is more likely to put some pep in your step and also you may lose weight.
I forget which dose is better for depression and which is better for ADHD. But there is also the SR vs ER thing.

A Virgin ADHD brain - one not tainted by years of drug use - may find WB very helpful for focus and all that but one good thing I’ve found is it doesn’t make me gain weight. Unlike the demon Lexapro did and took me 8 months to get my metabolism untucked.

Oh and a virgin brain (or at least not a brain that’s been through the wringer) may also find it to be somewhat euphoric. Or so Ive heard. Ooh to be so lucky to create this Reddit thread: “Does WB make anyone else feel like Superman?”

Click to expand...

This is not absolutely suggested or anything, but there is something called Ephedrine, I mentioned it Earlier in the Thread. There are Drug Interactions where the Enzymes for Ephedrine and the Enzymes for Wellbutrin, are Blocked by the Other. So, You take Wellbutrin and it Blocks the Breakdown of Ephedrine, so Your Ephedrine Bloodlevels stay Higher for longer. Then if You take Wellbutrin, or take them at the same Time, the Ephedrine Blocks the Breakdown of the Wellbutrin. Now, there is Plenty of Evidence that Wellbutrin can cause Seizures, there are a Good number of Erowid Entries about Wellbutrin and then there are Articles like one for example calls Wellbutrin “The Poor Man’s Cocaine” and talks about someone that was Snorting the Pills, Crushed up, and they had a Seizure, at which Time the Doctors Discovered that this was the Cause. And the Bloodlevels are what Cause Seizures.

And there is Research on Ephedrine, People have Heart Attacks, it is now Found as “Bronkaid” which is behind the Counter in America, so You have to be 18 to Buy it and they Scan Your ID to see how often You are Buying it because it is used to make Methamphetamine. Ephedrine is related to Psuedo-Ephedrine, which is in Sudafed which is more well known as a Meth Ingredient. But if You are actually taking the Pills You aren’t doing anything Wrong. Ephedrine is also Found in Ephedra Grass, Mormon Tea it is called, and the Mormons use this because Caffeine is banned for Mormons. Again, this Substance does Cause Heart Attacks, it used to be all over the Place. This stuff kind of Works as a Miracle Diet Pill because You can not Eat for Hours and Hours, and You don’t Feel Hungry at all. You can go 12-24 Hours without Eating Easily by eating a Bronkaid or a half a Bronkaid every 4 Hours or so. It isn’t like Caffeine, which acts on the Xanthene Receptors, and instead Ephedrine Works on Dopamine and Norepinephrine. You can Fail and Drug Test for Meth from taking Ephedrine, and for that Matter Wellbutrin can actually show up as Amphetamines in a Urine Test. This stuff was Regularly used in Gyms to make Working out more Enjoyable and to give the person Energy, etc, it is an Actual Performance Enhancing Drug, it Clears the Airways. It has been a Miracle Asthma Cure since the 50s, and that is why Bronkaid exists, it is still Legal to Sell it as Asthma Medicine. But over the Last 20 Years the FDA banned Ephedrine for use in Weightloss and Workout Supplements, because of the Number of Heart Attacks Caused by Ephedrine use in America.

I just want to Point out that this exists, and also anyone using the Raw Grass to make Tea should be Careful if also using Wellbutrin, and just be Careful Generally. Bronkaid exists after nearly 2 Decades of Heavy Regulation, it is Dosed at Very Safe Levels. You can Safely take even like 4 Bronkaid Pills at a Time after You take a Half of one or 1 to Test, or after a few Tests, not that You need 4, but the Point is that it’s Safe enough to do so. The Tea made from the Grass could be much more Potent depending how much Grass You use.

I have been taking Wellbutrin, as Prescribed, on and off now for about 6 Months, most of the Time I was not taking it, but I don’t notice a massive difference between using it and not. I do notice however that it does, as a Cathinone should, work similar to Caffeine but usually when taken by itself it actually causes a Period of Sleepiness before the stimulant effect. It seems, based on how it Works (so this is an Educated Guess), that what is happening is that the Dopamine and Serotonin Reuptake action causes a Person to feel Tired, as like Marijuana would, then the stimulant effect takes over later. And this is taken as Prescribed, Extended Release, I have bitten and broken it maybe 3 Times and didn’t notice a huge Difference.

This would be similar to how Thorazine Works, but Thorazine also has a Anti-Histamine effect if I’m not mistaken, and has an opposite activity profile to Wellbutrin. Thorazine Blocks Dopamine, but that causes a Spike in Dopamine Production leading to a Period of what many People describe as a Good Feeling, then it causes Sleep (an effect of Anti-Histamines and Dopamine), then it levels out Dopamine levels to a lower amount because it’s Blocking it and the Body finishes the spike in Dopamine Production.

Mixed with Ephedrine (usually Ephedrine First or at the same Time) 25mg, sometimes another Ephedrine dose later also, it definitely Works to help with Long Work Shifts. You could probably stay awake for Days, though I haven’t done that.

I usually Smoke Marijuana but haven’t been because of some Drug Tests I have to take for a while, and I have been using Mucuna Puriens occasionally and there aren’t really any problems, not that Marijuana is addictive but there is like Dopamine Syndrome and Things to be kind of concerned about so I thought I would mention it. I have thought about Adding Echinacea for CB Receptor purposes but have not done that.

I will be taking L-Methylfolate (which I have taken before) and Strontium soon, but that may not be of interest to some on this Forum, except that L-Methylfolate has Studies related to Depression and Schizophrenia related to Hair Loss that is kind of interesting.

I would also like to Add, that while I haven’t been taking large amounts, or snorting the Wellbutrin, I would like to add the comment that Wellbutrin and Ephedrine taken in these amounts, wouldn’t have much Recreational Value. I could see someone using it for Work, maybe as a Performance Enhancing Drug, but in these amounts I would not say there is a Recreational Value, it’s not Euphoric, You could maybe say that it is depending on the Person, but I didn’t have any kind of Euphoric Rush or anything like that. And again, I’m just taking it as Prescribed and used Small amounts of Ephedrine.

Now, with the Enzyme activity of both having kind of like a Nutmeg Enzyme Profile (there are 2 Molecules in Nutmeg, one is spelled like Mystricin, and the 2 Molecules taken alone do nothing, but together they give Nutmeg the ability to make You feel Drunk), I would assume that there is some kind of “Oilahuasca” that can be made with this.

From Dr. Sasha Shulgin in the Book “PIHKAL”:

This is a material that might be a contributing factor to the pharmacology of nutmeg. The major essential oil from that spice is
myristicin, and it is the easiest source of MMDA. It has been reported that the passage of this oil through the liver of a rabbit will generate MMDA in that animal. The only difference between the two molecules, structurally, are the elements of ammonia.
Myristicin plus ammonia gives MMDA. Another natural source of myristicin is Oil of Parsley, which is also an excellent source of
apiole, mentioned under DMMDA
. A rumor that had currency in the 1960’s, that parsley could get you high, probably had its origins in the reports of myristicin being present, coupled with myristicin being the principal source of MMDA. The relationship to myristicin (an essential oil) led to the classifying of MMDA as an Essential Amphetamine. These relationships are expanded upon, under TMA.