I am a long time reader of this page and a first time poster. I have lyme disease. This causes large amounts of pain. I currently use 10hy/325 several times per day and it really only keeps the pain away for maybe two hours. The docs aren't very kind to me in regards to pain. They seem to really love tram which does nothing for me. I have tried to find a pain clinic but most of them have been shut down. I am trying to figure out what my next step should be. I feel like a longer acting relief would be best. I am unable to afford paying online. I grow mmj and that helps with sleep and anxiety but doesn't cut it for pain. My state is very restrictive on pain meds but is generous with mmj. Any words of wisdom much appreciated.