Nootropics?

Acecard

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Jul 28, 2011
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Anyone here open to discussing nootropics?  I have a lot of research and am fascinated by the them.  Some are excellent some so-so.  Lets get a discussion going.

 
What Are Nootropics?

Nootropics are “smart drugs†that improve mental functions such as memory, intelligence, motivation, attention, concentration, and cognition. These “smart drugsâ€, range from drugs constructed in

laboratories, all the way to natural supplements and plants that have been discovered to have nootropic benefits. It is important not to be misled by the idea of nootropics. They are not going to turn you into a genius overnight. You aren’t going to take one and all of a sudden know advanced calculus. However, if you stick to a balanced nootropic regimen you will notice a difference. You will feel more motivated, more focused, and have a much easier time remembering things while promoting good mental health all at the same time.  It is perfectly natural to be a skeptic when it comes to nootropics.

After all, if a pill could make you smarter, more focused, or more motivated, then why isn’t everyone taking it? Many skeptics fall into the fallacy, “If it’s too good to be true, it probably isâ€. If everyone

were to pass on things that appeared “too good†then one would miss out on a lot of opportunities. Even though skepticism is healthy, it is important to conduct your own research, and form your own opinion. When one looks into the possibility of smart drugs on a deeper level, it becomes apparent that not only are smart drugs plausible, but that science has proven their existence and their benefits to humanity as a whole.

In order to understand the plausibility of nootropics one must first understand exactly how the human brain processes information. The cerebral cortex of the human brain may contain anywhere from 20 billion- 1 trillion neurons. Each of these neurons can then be linked up with as many as 10 billion synaptic connectors. When your brain receives any sort of input these neurons communicate to their respective connector using a combination of different chemical neurotransmitters. One commonly known neurotransmitter is dopamine. Dopamine acts upon the reward system of the brain causing feelings of enjoyment and motivation.

In many cases, depression is the result of low levels of dopamine. A common trait among people with social anxiety is a poorly functioning D2 Dopamine receptor causing low dopamine levels.

Every person’s state of mind at any particular time is linked to the levels of different neurotransmitters. For example, alcohol increases levels of the neurotransmitter GABA and lowers the level of Glutamine.

As your brain receives more GABA and less Glutamine, you become more sluggish, lose your ability to reason, lose your ability to concentrate, and your motor skills decline. Adderall is an example of the opposite.  It affects the neurotransmitters dopamine and norepenephrine. Larger levels of dopamine cause a feeling of arousal and alertness while increased levels of norepenephrine cause increased mental clarity and focus. In fact, because of adderall’s effects the illegal consumption of it has skyrocketed in recent years among college students.

Everyone tries to reach their full potential, but not everyone succeeds. Nootropics will help you reach that full potential. I firmly believe that one day nootropics will be taken as commonly as coffee to give people an edge. 

 


Why Take Nootropics?
There is no denying that everyone wants to be smarter. Realizing you want to be smarter isn’t the tricky part. The tricky part is actually doing it. Improving your memory, your focus, and your ability to learn does not come easy. Some people work hard each and every day hoping to make dean’s list, or hoping for that next promotion. If there were a way to improve your chances at success simply taking a completely safe and non-reliant supplement, wouldn’t you take it?

Improved mental functions aren’t the only reason to take nootropics.  After all, what would be the point of improving your memory, focus, and motivation if it depleted your brain faster? Luckily for us, the opposite is true of nootropics. Many nootropics were developed to help people with mental disorders such as Alzheimer’s and schizophrenia but were later discovered to benefit healthy individuals as well. Not only do certain nootropics help protect you against disorders such as these, but some also slow the aging process that takes place in your brain. If another goal of yours is staying as sharp as possible for as long as possible, then nootropics will help.

There is a wide variety of completely safe supplements available for your use. Whether you want to use completely natural supplements, man made supplements, or both, the option is there. This is an opportunity not many people really explore, and it would be a shame for you to miss out. Nootropics will help you reach your full potential and achieve success in your future endeavors.

 


How Do Nootropics Work?
There are many different kinds of nootropics. It would be near impossible to explain how every single one works in one article.

However, there are two very common mechanisms of action that nootropics use which I will explain, along with a rare, yet revolutionary mechanism

of action.

1. Many nootropics affect neurotransmitter levels within the brain

If you have read the introduction to nootropics above, then you already have a good idea of how this works. Simply put, your brain is driven by levels of neurotransmitters that your neurons distribute to a multitude of synaptic connectors in your brain. There is a wide variety of these neurotransmitters and they act as your brain’s way of communicating with itself.

Communication between these neurotransmitters and their connectors result in certain outputs such as a mood, a feeling, or a thought.

Increasing or decreasing the levels of these chemicals in the right way can result in quicker and more efficient communication within the brain.

This results in increased focus, clarity, memory, and learning. Think of your brain as a factory, the workers as neurons, and the neurotransmitters as the product. Simply put, some nootropics allow your workers to make more products in the same amount of time.

2. Many nootropics increase the flow of oxygen to your brain

Think of oxygen as fuel for your brain and body. Your brain not only uses this fuel but acts a hub, distributing it to other parts of your body. The decrease of oxygen to any body part is called hypoxia while the complete lack of oxygen is termed anoxia. Symptoms of mild hypoxia may include lack of concentration and lack of coordination.

Prolonged hypoxia and complete anoxia can result in permanent brain damage and death. Complete lack of oxygen can result in death in as little as 4-5 minutes.

When your brain is receiving sufficient levels of oxygen it distributes it to life-support functions first, such as your heart, and then to higher level functions such as your memory. This means that when your brain’s intake of oxygen increases, the extra oxygen goes straight to the higher level brain functions. This leads to improved memory and concentration among other things. In retrospect, when oxygen flow decreases, these higher levels functions are the first things that lose oxygen.

Let’s go back to the factory example. Oxygen is what is powers your factory. When your factory has no oxygen the power goes out and the machines stop running. When you have excess oxygen the lights are brighter and the machines run.

3. Few nootropics increase your neuron growth factor (NFG)

Some people have heard growing up that you cannot create new brain cells. There was a time when this was a common belief but science has since disproved this rumor. Rita Levi-Nontalcini and Stanley Cohen discovered the neuron growth factor in the 1950′s and after gaining recognition, won a Nobel Prize in 1986 for their discovery. The neuron growth factor is a metric used to gauge the growth and maintenance of certain neurons.

Think of the factory example one last time. Remember those workers that are producing products for your brain. Well as in any factory, workers retire and workers are hired. When it comes to your brain,workers are hired less quicky then they retire hence the mental breakdown that results from aging. Certain nootropics can actually hire workers at a faster rate. This promotes overall mental health and can actually slow the mental breakdown that results from aging.

 
Have you heard of selank? It's injectable (legal as well) and its a peptide to help with anxiety and very similar to nootropics

 
Yes I have heard of selank, it is very interesting and I will post some info I have on it shortly

 
Are there any negative side effects? My memory is seriously the worst (and that was before I started taking ambien!) My problem-solving skills and emotional intelligence are eking upward as I age, but memory—literally—fuhgeddaboutit.

 
Are there any negative side effects? My memory is seriously the worst (and that was before I started taking ambien!) My problem-solving skills and emotional intelligence are eking upward as I age, but memory—literally—fuhgeddaboutit.
Not an easy question.  Nootropics can have different effects depending on the individual.  I take ambien nightly and don't feel it as any adverse effects.  What specifically are looking to achieve and I can perhaps give some recommendations, it might take a little bit of experimenting to find what is right for you.

 
Hi! I've been taking Nootropics for a while and am currently taking:

Piracetam - 3.2-4g in the morning, and 3.2-4g with lunch.
Aniracetam - 750mg in the morning, and 750mg with lunch.
Pramiracetam - 300mg in the morning, and 300mg with lunch.
L-Theanine - 200mg in the morning, and 200mg with lunch.
Caffeine - 125mg throughout the day.

Sulbutiamine - 200mg in the morning.
CDP-Choline - 250mg with lunch, and 250mg after dinner.
Nicotine - Half a pack a day.


I'm definitely down to discuss about Nootropics, I know a bit about them however I am by no means a Nootropic Guru

 
Hi! I've been taking Nootropics for a while and am currently taking:

Piracetam - 3.2-4g in the morning, and 3.2-4g with lunch.

Aniracetam - 750mg in the morning, and 750mg with lunch.

Pramiracetam - 300mg in the morning, and 300mg with lunch.

L-Theanine - 200mg in the morning, and 200mg with lunch.

Caffeine - 125mg throughout the day.

Sulbutiamine - 200mg in the morning.

CDP-Choline - 250mg with lunch, and 250mg after dinner.

Nicotine - Half a pack a day.

I'm definitely down to discuss about Nootropics, I know a bit about them however I am by no means a Nootropic Guru
You are definitely doing a regimen!  What is your feedback on this?  Strangely I've heard of nicotine as a noop.  I don't smoke but do use nic in smokeless form - switched from highly toxic American chew to swedish snus which claims to have less additives.

 
Haha yea, it's my Social Anxiety and Cognitive boost regimen for the school year.

Well the stack seems to be working quite well to be honest. It had initially started out with just Piracetam in December of '11, and by February I had added Aniracetam to the stack. The Piracetam worked pretty well by itself , I noticed in the two months that I was taking it alone that I was able to recall things a bit more sharply. I also noticed what I could only describe as photo-sensitivity in regards to lights and colours after taking Piracetam the first several days.


I added the Aniracetam due to its reported anti-anxiety benefits as well as the fact that it would be stimulating the AMPA receptors which was something that Piracetam wasn't doing. The Pramiracetam was added after talking to the vendor who I ordered through and discussing their other products and what would be advicable to add to my stack.

Nicotine is supposedly a Nootropic, and when I'm on Piracetam I definitely can tell that the Nicotine kickstarts the Piracetam into a higher gear. Supposedly the two are synergistic, so if you smoke/dip/chew/vape some Nicotine while on Piracetam you should get more pronounced effects.

 

 
So Acecard what all are you stacking, and how has your own Nootropic journey been?

 
Actually I have just been struggling with kicking the nicotine and think I have succeeded.

As far as noops I am presently taking Alpha GPC, sulbutiamine, Noopept, Aswagandha, Lion's mane, niacin, & I pin a B complex.

I'm thinking I could do better and am interested in your stack, I have piracetam but it is in powdered form and I hate trying to chug it down.

 
Congrats to that mate, I've tried a few times to kick the nico habit, but caved everytime.

Yea, the Racetams all taste like chemical warfare. There was only one concoction I was able to conjure to help mask the taste of Piracetam and that was making a cup of coffee, black (like pitch black) and mixing it in once the coffee had cooled down a bit and then slugging that back. It really doesn't taste that great but if you get some condenced milk (sweetened) and put it in the bottom of your mug before adding the coffee you can actually enjoy it with out making a face hahah.

For the fat soluble ones, you can try making a smoothie, blend up a bunch of your fave fruits, some spinach, and use either whole milk or some almond milk. And just put your doses in there, blend it. Make sure to fill up the whole blender though, because mixing all the fat solubles into a single glass is going to be...terrifying.

You should consider possibly adding L-Theanine or Centrophenoxine. I recently got started on Centrophenoxine in the last couple of weeks, and I have to say it's pretty decent and have been alternating between it and CDP choline.

Sorry for the long delay mate, I only get a chance to sit down on my computer every so often.

 
Actually trying phenylparacitam now I will report back, has some great reviews on amazon

 
I think provigil is a Nootropic and after reading a lot about it I tried it.

I live in an area that has less then 70 days a year with any amount of sun, the rest is low fog/smog/pollution that is always present and i think the lack of sun has messed up my sleep/waking cycle. Here it is Like SF but longer periods of fog/smog and more of it. I felt terrible for years and just off, didn't sleep well, always tired, and no energy or motivation.

I tried provigil about two months ago and it changed my life! I sleep well, feel awake, do things again like hobbies I had set aside and I am a happier person. I had not had dreams for 20 years, or very few, and now I dream almost every night.

My wife and my brother tried them and said, yea their so so and no big deal but helped them do more at work.

My point is they affect me very different then they affect them. For me they gave me my life back and I feel like I did in my late teens attitude and motivation wise.

They are not addictive and I never feel like taking more then 200mg each morning.

Good stuff.

 
Hi! I've been taking Nootropics for a while and am currently taking:

Piracetam - 3.2-4g in the morning, and 3.2-4g with lunch.

Aniracetam - 750mg in the morning, and 750mg with lunch.

Pramiracetam - 300mg in the morning, and 300mg with lunch.

L-Theanine - 200mg in the morning, and 200mg with lunch.

Caffeine - 125mg throughout the day.

Sulbutiamine - 200mg in the morning.

CDP-Choline - 250mg with lunch, and 250mg after dinner.

Nicotine - Half a pack a day.

I'm definitely down to discuss about Nootropics, I know a bit about them however I am by no means a Nootropic Guru
just curious, are alot of these loaded in caffeine?  this is something GNC would carry correct?

 
Nootropics I am currently trying out:

Phenylpiracetam

L-theanine (night)

Galantamine (night)

Choline (night)

St. John's Wort

Picamilon

Ashwagandha

Brahmi

Mentat

Rhodiola Rhosea

Brain Amino Acid blend

Grape seed extract

Basil extract

Turmeric extract

Lemon Balm extract (night)

Nicotine

Still new to the supplement world and thus experimenting with timings and dosage to find a suitable combination.

Looking to add a strong script to boost the effects of all herbs... Any suggestions? No amphetamines or ritz though. I have heard Modafinil or ephedrine work. Anyone used them? What about noopept or piracetam instead of phenylpiracetam?

Also, has anyone tried huperzine A?

 
Last edited:
@JustChillin

Nah, none of the supplements I take have caffeine in them unless I stop at a local vitamin shoppe and grab something with it in it really fast.

@Devil

That is a nice looking stack, as to a strong script I wouldn't be too sure about that. Have you considered trying to add either Piracetam or looked into Sunifiram? Piracetam I've had some experience with along with noopept and can say they are both effective nootropics. Piracetam is always a part of any nootropic stack that I am taking/working on, due to its varying benefits that are hard to find in other nootropics together. Noopept+Oxiracetam+Phenylpiracetam taken with coffee, is one of the strongest immediate stacks I have taken before a study.

 
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