Can benzo’s be stored indefinitely under the right conditions?

[Rustyshakelford]

By indefinitely I mean a lifetime. Vacuum packing loose? Nitrogen injected sealed packaging? Factory sealed bottles? What’s the play here…

My thought would be take X# of factory sealed bottles of farmapram and kpins put in a food saver bag then putting them in the freezer…think I could get some decades with that tec? Is there a better way? Im building a stockpile for life. I don’t want to buy regularly ever again once I get enough quality sealed bottles. 

Any ideas for longgg term storage much appreciated 

 

[Prazzin45]

By indefinitely I mean a lifetime. Vacuum packing loose? Nitrogen injected sealed packaging? Factory sealed bottles? What’s the play here…

My thought would be take X# of factory sealed bottles of farmapram and kpins put in a food saver bag then putting them in the freezer…think I could get some decades with that tec? Is there a better way? Im building a stockpile for life. I don’t want to buy regularly ever again once I get enough quality sealed bottles.

Any ideas for longgg term storage much appreciated

I wish this thread got more interested. I’d also like to know. Did you find anything out?

 

[Lucifereatspi]

By indefinitely I mean a lifetime. Vacuum packing loose? Nitrogen injected sealed packaging? Factory sealed bottles? What’s the play here…

My thought would be take X# of factory sealed bottles of farmapram and kpins put in a food saver bag then putting them in the freezer…think I could get some decades with that tec? Is there a better way? Im building a stockpile for life. I don’t want to buy regularly ever again once I get enough quality sealed bottles.

Any ideas for longgg term storage much appreciated

From my studies, I would say sealed bottles is fine. Just want to insure that moisture doesn’t become an issue or fluctuating temperatures. So you could seal them in a bag and put them in the fridge. Antibiotics or like liquids reactive to light you’ll have to worry more about. I’m not sure I can link papers to the forum but I can provide the evidence discussing that expiration dates are more of a ploy on most medications.

 

[Izzyhuahua]

I work in pharma and you probably don't want to freeze or refrigerate them unless the package insert says freezing or refrigerated storage is acceptable. You don't just have to worry about the ALP, you have to consider the excipents (other ingredients). At pharma companies, we have to carry out freeze/thaw and temperature excursion studies to support approval and that info goes directly the package insert.

I couldn't find a PI for Farmpram but Pfizer's instructions state: "store at room temperature 20C to 25C (68 to 77F). [See the USP]"

Now that USP statement is important. I have access to USP online and USP defines Room temperature (also referred to as ambient temperature) as "The temperature prevailing in a working environment." Controlled room temperature (which is what is important to us": The temperature maintained thermostatically that encompasses the usual and customary working environment of 20°–25° (68°–77° F). The following conditions also apply. Mean kinetic temperature not to exceed 25°. Excursions between 15° and 30° (59° and 86° F) that are experienced in pharmacies, hospitals, and warehouses, and during shipping are allowed. Provided the mean kinetic temperature does not exceed 25°, transient spikes up to 40° are permitted as long as they do not exceed 24 h. Spikes above 40° may be permitted only if the manufacturer so instructs. Articles may be labeled for storage at “controlled room temperature” or at “20°–25°”, or other wording based on the same mean kinetic temperature [see also Good Storage and Distribution Practices for Drug Products á1079ñ, Quality Management System, Environmental Management System, Mean Kinetic Temperature (MKT) Calculation]. An article for which storage at Controlled room temperature is directed may, alternatively, be stored and shipped in a cool place or refrigerated, unless otherwise specified in the individual monograph or on the label.

So if it COUDN'T be refrigerated, it should be in the packaging but in reality, there's not a SHORT-TERM issue with refrigerated storage.

The three biggest threats to stability are moisture, light, and temperature. I would put them in the food saver packaging, keep them in a dark place, and you should be good to go!

 

[Lucifereatspi]

I work in pharma and you probably don't want to freeze or refrigerate them unless the package insert says freezing or refrigerated storage is acceptable. You don't just have to worry about the ALP, you have to consider the excipents (other ingredients). At pharma companies, we have to carry out freeze/thaw and temperature excursion studies to support approval and that info goes directly the package insert.

I couldn't find a PI for Farmpram but Pfizer's instructions state: "store at room temperature 20C to 25C (68 to 77F). [See the USP]"

Now that USP statement is important. I have access to USP online and USP defines Room temperature (also referred to as ambient temperature) as "The temperature prevailing in a working environment." Controlled room temperature (which is what is important to us": The temperature maintained thermostatically that encompasses the usual and customary working environment of 20°–25° (68°–77° F). The following conditions also apply. Mean kinetic temperature not to exceed 25°. Excursions between 15° and 30° (59° and 86° F) that are experienced in pharmacies, hospitals, and warehouses, and during shipping are allowed. Provided the mean kinetic temperature does not exceed 25°, transient spikes up to 40° are permitted as long as they do not exceed 24 h. Spikes above 40° may be permitted only if the manufacturer so instructs. Articles may be labeled for storage at “controlled room temperature” or at “20°–25°”, or other wording based on the same mean kinetic temperature [see also Good Storage and Distribution Practices for Drug Products á1079ñ, Quality Management System, Environmental Management System, Mean Kinetic Temperature (MKT) Calculation]. An article for which storage at Controlled room temperature is directed may, alternatively, be stored and shipped in a cool place or refrigerated, unless otherwise specified in the individual monograph or on the label.

So if it COUDN'T be refrigerated, it should be in the packaging but in reality, there's not a SHORT-TERM issue with refrigerated storage.

The three biggest threats to stability are moisture, light, and temperature. I would put them in the food saver packaging, keep them in a dark place, and you should be good to go!

Very informative. Nice write up.

 

[Pharmia]

Most pills can be stored indefinitely in sealed containers in a cool dry area AFAIK. I'd recommend also perhaps using brown/dark-tinted glass jars to limit any possible degradation from exposure to light, and put some of those desiccant packs that sometimes come in supplement bottles in there, and you should be good to go.

 

[Strongbull]

By indefinitely I mean a lifetime. Vacuum packing loose? Nitrogen injected sealed packaging? Factory sealed bottles? What’s the play here…

My thought would be take X# of factory sealed bottles of farmapram and kpins put in a food saver bag then putting them in the freezer…think I could get some decades with that tec? Is there a better way? Im building a stockpile for life. I don’t want to buy regularly ever again once I get enough quality sealed bottles.

Any ideas for longgg term storage much appreciated

Yes, separate into quantities of 500 pills. Then store in military grade aluminum airtight containers with threaded end caps.

Place two silica moisture absorbing packs and two oxygen absorbing packs into each container with your pills.

You do not want to vacuum seal because you want to store under a nitrogen atmosphere.

Finally store the sealed container under refrigerated temperatures.

These conditions will prevent any degradation of your medicine for greater than 1000 years.

 

[trinity]

I work in pharma and you probably don't want to freeze or refrigerate them unless the package insert says freezing or refrigerated storage is acceptable. You don't just have to worry about the ALP, you have to consider the excipents (other ingredients). At pharma companies, we have to carry out freeze/thaw and temperature excursion studies to support approval and that info goes directly the package insert.

I couldn't find a PI for Farmpram but Pfizer's instructions state: "store at room temperature 20C to 25C (68 to 77F). [See the USP]"

Now that USP statement is important. I have access to USP online and USP defines Room temperature (also referred to as ambient temperature) as "The temperature prevailing in a working environment." Controlled room temperature (which is what is important to us": The temperature maintained thermostatically that encompasses the usual and customary working environment of 20°–25° (68°–77° F). The following conditions also apply. Mean kinetic temperature not to exceed 25°. Excursions between 15° and 30° (59° and 86° F) that are experienced in pharmacies, hospitals, and warehouses, and during shipping are allowed. Provided the mean kinetic temperature does not exceed 25°, transient spikes up to 40° are permitted as long as they do not exceed 24 h. Spikes above 40° may be permitted only if the manufacturer so instructs. Articles may be labeled for storage at “controlled room temperature” or at “20°–25°”, or other wording based on the same mean kinetic temperature [see also Good Storage and Distribution Practices for Drug Products á1079ñ, Quality Management System, Environmental Management System, Mean Kinetic Temperature (MKT) Calculation]. An article for which storage at Controlled room temperature is directed may, alternatively, be stored and shipped in a cool place or refrigerated, unless otherwise specified in the individual monograph or on the label.

So if it COUDN'T be refrigerated, it should be in the packaging but in reality, there's not a SHORT-TERM issue with refrigerated storage.

The three biggest threats to stability are moisture, light, and temperature. I would put them in the food saver packaging, keep them in a dark place, and you should be good to go!

Thank you finally, common sense.

Exp dates is all about ££££ not efficacy or degradation which occurs in liquids at a very small rate unless recombinant in nature, peptides etc. Again all based on external factors sunlight, storage temps etc.

We are still using a homebrew methenolone enanthate from 2007 made specifically for us and stored correctly with full potency.

Its all a scam.

 

[trinity]

All the posts have common sense being applied