Codeine vs tramadol

[Tttddx]

Hi 

Not sure i have this in the correct place. How similar are these 2 tablets? If I'm really used to codeine but suddenly switch to tramadol will my body give out? Or are they quite similar in mechanism? 

 

[KittyPurffect]

Personally I don't compare the 2, ever. Codeine makes me sleepy, relaxed, slightly euphoric and nauseous (barely to bother). Tramadol makes my head feel, numb? Or cloudy, slightly euphoric and a bit anxious. But you probably won't feel any withdraws from codeine if you take Tramadol.

 

[Phrenicz]

Hi 

Not sure i have this in the correct place. How similar are these 2 tablets? If I'm really used to codeine but suddenly switch to tramadol will my body give out? Or are they quite similar in mechanism? 

Hey there! 

They are similar, although whereas Codeine is a true opioid, Tramadol is a synthetic opioid... But they still effect the same receptors in the brain... However, Tramadol does inhibit the reputable of serotonin and norepinephrine, so it's kind of like adding an antidepressant to the mix?..  And that's the side of Tramadol that doesn't agree with everyone? It also has a much longer half life, due to it's SNRI properties...

Some people do find this helpful, as it definitely has certain mood lifting qualities, and slightly longer analgesic effects? However, I think the latter is due to the parallel SNRI properties that are also occurring... Resulting in an almost placebo like effect, of your slightly elevated mood, masking the propensity to feel your pain? 

However, if you have the choice and need to be on either long term, then I'd personally stick with Codeine... You will almost certainly develop a tolerance and dependence for either, that goes without saying... But ask almost anyone which one they'd rather withdraw from and they'd definitely choose Codeine?! Tramadol withdrawals are a real motherfucker!! It's like opiate & antidepressant withdrawal, both at the same time... Quite simply, it's fucking horrible!! Give me a good old Codeine withdrawal any day ; )

~P~

 

[javaman]

Interesting info @Phrenicz, I didn't know that about Tramadol. That may explain why I've never liked it! I tend to get terrible insomnia when I take it, regardless of time taken during the day. I could take it at noon, but as soon as I try to go to bed I have extremely vivid, almost waking dreams. Kind of like daydreaming, but half asleep, and unable to fall completely asleep. It's really not pleasant at all. I recently had a doc try to prescribe Trams and I told him about this, so he prescribed codeine instead. They didn't do much for the pain, maybe a little better than acetaminophen and ibuprofen alone, but not much. No weird side effects though.