Leucine

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Although it has been well established that leucine consumption during and after resistance exercise promotes muscle growth, the verdict is still out regarding the performance-enhancing effect from leucine consumption before training. Some of the uncertainty about leucine's pre-workout consumption stems from the fact that leucine consumption decreases energy production within the muscle cell, potentially diminishing muscle performance during exercise. Another concern about pre-workout leucine consumption involves the likely desensitization of the potent muscle-building hormone insulin, resulting from additional leucine consumed before working out. The final concern involves the negative influence that leucine consumption may have on the central nervous system (CNS) where pre-workout leucine consumption might increase the rate of CNS fatigue, promoting overall sluggishness that decreases exercise performance.