PYNAZOLAM

some reports on reddit - supposedly good for sleep between 0.5 - 2mg with a relatively higher threshold for blacking out. doesn't seem to have much recreational value. claims that you need to be a little bit more careful with interactions on other mags using this one because of difference in receptor site binding compared to other benzos but I can't personally vet the validity of that claim.
 
That’s odd I tested 4 mg last night, along with my usually dosage of 20mg ethylbrom (taken earlier) and I did feel some effects at 4mg, felt like a happy benzo feeling very subtle although. Don’t know need to research it some more. And yeah I’ve read about receptor thing but have no clue what any of it means!
 
Re: receptor site binding I think there was some speculation of it having some affinity for ser0t0nin receptors iirc. Which if true would mean be careful reading it with certain ser0t0ninergic mags and avoid reading it with MAOI mags, among other precautions. But similar to xenra I have no way to vet that claim's validity. Unsure if there is any other speculation about this one in terms of which specific GÃBÂ Ã receptor sites it has the most affinity for but I am admittedly not particularly knowledgeable about the differences between GÃBÃ A1 vs A2, A3, A4, A5 etc.
 
Most people prefer "-Lam" benzos which act mainly on a1 (addiction, amnesia, sedation, delusions of sobriety) and a5 (loss of executive function, the only site ethanol touches)

It does not fit into a1 , no affinity for a5, possible a3 (muscle relaxation) and a4 (antiepileptic). Sedative and those without dependence will find much stronger effects. Intended to more heavily affect 5ht in the way all 7-nitro bzd's do at high doses,. Affects stimulants physiological effects different than traditional benzos.

All nitro-bzds have a much smaller therapeutic index, this one may be even lower than clonazepam's ~250mg LD50. May significantly increase respiratory depression relative to intensity of pynazolam's effects.
 
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