Separate two chemicals using chemistry regarding Medetomidine/bromazolam pressed pills.

[MrFuszy]

Dissolve the Mixture:
Dissolve your mixture in a water-immiscible organic solvent like Dichloromethane (DCM) or Ethyl Acetate.
Wash with Acid: Wash the organic solution with a mild, dilute aqueous acid (such as 0.1 M to 1 M Hydrochloric Acid).
What happens: The basic imidazole ring on the Medetomidine will become protonated (charged) and turn into a water-soluble salt.
It will move completely into the top aqueous layer.

The result: Bromazolam, being a very weak base, will remain unprotonated and stay dissolved in the bottom organic layer.Separate and Recover:

For Bromazolam: Separate the organic layer, dry it with a drying agent (like Magnesium Sulfate), and evaporate the solvent to recover the Bromazolam.

For Medetomidine: Take the acidic aqueous layer, neutralize it by adding a base (like Sodium Bicarbonate) until the pH is basic, and extract it again with fresh organic solvent.
Dry and evaporate to recover the Medetomidine.

 

[MrFuszy]

So for me I have a 250ml round bottom flask, which i will be using to hold the crushed into 1 powder, this will consist of 40 pills.
Once im done with my little project I'll come back with the results.