War on drugs! Suck on this!

mhzjunkie

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Discovery opens door for homemade pain pills

Los Angeles, CA (AP) Scientists have figured out all the steps to make morphine and similar painkillers without using opium poppies, opening the door for home-brewed drugs and potential abuse.

While no one has yet reported making morphine in the laboratory from scratch, some experts are calling for regulations to prevent garage tinkerers from making do-it-yourself drugs.

Society needs to “think this through now before it becomes a reality,” said bioengineer John Dueber of the University of California, Berkeley, who led a team that discovered the final missing link of the process.

Poppy plants have been farmed for centuries for opium, from which morphine is derived. The controlled substance is often used before and after surgeries to relieve severe pain.

For the past decade, various groups of researchers have hacked the DNA of yeast to mimic poppies, in hopes of creating cheaper and less addictive pain relievers. So far, the yeast strains created can only perform the last steps of a long process that can lead to morphine and other narcotic drugs.

A team led by researchers at UC Berkeley discovered the missing piece — the first step in the process — and published the findings Monday in the journal Nature Chemical Biology.

The genetically engineered yeast was able to convert sugar to a chemical that’s a precursor to morphine. While the researchers stopped short of producing the drug in the lab, their work lays the foundation for DIY narcotics without the need to grow poppies.

Experts said it’s still extremely difficult for people to make homemade morphine because the process is inefficient. Even scientists are years away from lab-made morphine that’s strong enough to treat pain.

With technology advancing, some point out that there could come a time when brewing morphine may be as simple as brewing beer.

In a commentary published in the journal Nature, a group of researchers from the Massachusetts Institute of Technology and University of Alberta in Canada called for restricting genetically modified yeast strains to licensed facilities so that they won’t fall into the wrong hands. They also want current laws to be extended to make such yeast strains illegal to distribute.

Now is the time to act because “you don’t want to be doing it afterward. You can’t do it afterward,” Kenneth Oye, lead author of the commentary and director of the MIT Program on Emerging Technologies, said in a telephone interview.

Others said more discussion is needed to determine what regulatory controls should be in place.

“While there are risks of not acting quickly enough on modifying regulations during early technical development, there are also risks of too hastily solving the wrong problems,” Megan Palmer of the Center for International Security and Cooperation at Stanford University said in a statement.

Los Angeles, CA (AP) Scientists have figured out all the steps to make morphine and similar painkillers without using opium poppies, opening the door for home-brewed drugs and potential abuse.

While no one has yet reported making morphine in the laboratory from scratch, some experts are calling for regulations to prevent garage tinkerers from making do-it-yourself drugs.

Society needs to “think this through now before it becomes a reality,” said bioengineer John Dueber of the University of California, Berkeley, who led a team that discovered the final missing link of the process.

Poppy plants have been farmed for centuries for opium, from which morphine is derived. The controlled substance is often used before and after surgeries to relieve severe pain.

For the past decade, various groups of researchers have hacked the DNA of yeast to mimic poppies, in hopes of creating cheaper and less addictive pain relievers. So far, the yeast strains created can only perform the last steps of a long process that can lead to morphine and other narcotic drugs.

A team led by researchers at UC Berkeley discovered the missing piece — the first step in the process — and published the findings Monday in the journal Nature Chemical Biology.

The genetically engineered yeast was able to convert sugar to a chemical that’s a precursor to morphine. While the researchers stopped short of producing the drug in the lab, their work lays the foundation for DIY narcotics without the need to grow poppies.

Experts said it’s still extremely difficult for people to make homemade morphine because the process is inefficient. Even scientists are years away from lab-made morphine that’s strong enough to treat pain.

With technology advancing, some point out that there could come a time when brewing morphine may be as simple as brewing beer.

In a commentary published in the journal Nature, a group of researchers from the Massachusetts Institute of Technology and University of Alberta in Canada called for restricting genetically modified yeast strains to licensed facilities so that they won’t fall into the wrong hands. They also want current laws to be extended to make such yeast strains illegal to distribute.

Now is the time to act because “you don’t want to be doing it afterward. You can’t do it afterward,” Kenneth Oye, lead author of the commentary and director of the MIT Program on Emerging Technologies, said in a telephone interview.

Others said more discussion is needed to determine what regulatory controls should be in place.

“While there are risks of not acting quickly enough on modifying regulations during early technical development, there are also risks of too hastily solving the wrong problems,” Megan Palmer of the Center for International Security and Cooperation at Stanford University said in a statement.

http://www.wkyt.com/wymt/home/headlines/Discovery-opens-door-for-homemade-pain-pills--304427281.html

 
I read this, it excited me, but I don't think I have the know-how to make use of it, haha.

Poppies grow wild quite commonly, so, meh.

 
Drugbuyersguide Shoutbox
  1. xenxra @ xenxra: @WTF7218 it may as well be that way with how little effort some of the people on here make to find information that's exactly where you would expect it to be.
  2. ontovzik @ ontovzik: When I had long term shingles, lasting two months. All he could give me was a 10 day supply of dilaudid. He looked at the ground while we were talking about it. I could tell he was ashamed but it was the legislature and the governor that tied his hands. He was very upset that non-medical political people, the media, and the scared public were controlling how he treated his patients. Someday those people will need meds and a hospital bed and they will be gone.
  3. ontovzik @ ontovzik: I had a great doctor, he had the true gift of a healer and he stayed on top of all the science. He straight up told me that for many people opiods work for managing short and long term pain.
  4. ontovzik @ ontovzik: He peed it in the snow in my backyard.
  5. WTF7218 @ WTF7218: @xenxra 😆😂. Yes, but only a few brave souls will ever find the number. You must first order a Dirty Shirley from the bartender. Then you must discreetly take the cocktail napkin from under your drink and unfold it. There you will find the map to the location of the phone number, and clues to decipher the code that it is written in.
  6. xenxra @ xenxra: he left his phone number scribbled in a stall at the pub three blocks down
  7. N @ NYStateofMind: @Alkazar I would try one of those easy online ones .. reddit gives useful info about that
  8. Alkazar @ Alkazar: @NYStateofMind I dont really have a history of abusing things, my docotr is just really stingy. I am thinking of switching.
  9. C @ Cheesus: Thanks xenxra
  10. xenxra @ xenxra: @Cheesus yeah, use snote
  11. P @ psychedpsych: Trump is cracking down….
  12. P @ psychedpsych: Hackers are the scum of the earth
  13. N @ NYStateofMind: so it was easy bc of my history
  14. N @ NYStateofMind: I didnt really tell him but he knew I needed a new script since my dr went to jail
  15. N @ NYStateofMind: @xenxra I was on Adderall since 15 years ago so my dr prescribed that w no problems and then when I lost my best friend my doctor rxed the valiums but
  16. C @ Cheesus: Temp.pm down for anyone else?
  17. xenxra @ xenxra: @NYStateofMind my doctor's have always been pretty open minded if i can actually come in and explain the pharmacological action of the drugs im seeking instead of just telling them why i think i should be prescribed. the only time it didn't work out for me is when i was trying pharmaceuticals for depression ten years ago and suggested they let me try testosterone instead (turns out i was hypogonadal so they made a mistake denying my request at face value)
  18. T @ Testisthebest: Even down here in Florida when the pill mill docs all switched over to Suboxone and/or retired you can still find some pretty liberal docs but you gotta know what to look for. Mine does "pain management, detox, anxiety,etc. And no insurance. My doc writes me 60 5mg Valium, 14 2mg Xanax and asked if I had ever tried adderal to get more focus at work as I told him I run my own business.
  19. N @ NYStateofMind: @Alkazar do they know your history? Like I dont tell my doctor anything about myself except what they need to know,...I was able to get my dr to rx the highest dose of adderall along with valiums ..... if they dont know your history or there is no history I would just come out and ask what is the reason for their mistreatment.... they have no problem billing your insurance or taking a payment for the visit
  20. T @ Turbo259: @Layne_Cobain Thank you fam
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