xanax and tramadol combo?

[yngtxnes]

has anyone tried the two together? i have both right now and am curious what the effects would be like or if its just a waste of one of them because the other might overshadow the others effects? and idk about the doses i would use. if anyone has experience with this itd be appreciated

 

[PTFC]

Depending on your tolerance, if you do this, keep the dosage low tk begin with, main danger is depressing your central nervous system. Be cautious in any case. 

 

[GNA]

Good mix, I like it.

 

[kinsona]

@yngtxnes i have been taking tramz for about 15 years. First bought OTC whilst working in India and have continued to use them (sadly) on a daily basis since then. I tend to dose the tramz early morning 200mg single dose. Some times I reduce to 150mg and to be honest the effect is still as good. I enjoy the dual effects of the chilled out feel but with an energy like boost. For me onset is about 30-45 minutes. 6 hours duration max effect at about 120 minutes.  I use Barzz very infrequently, I find 1.5mg of a bar drops me like a brick. There is always a 10 hour gap in between the doses though. Tramz through the hepatic system is metabolized through the CYP2D6 enzyme. Xanax through the CYP3A4 & CYP3A5 enzymes.

Personally I use this info to tell me not to worry too much about serotonin syndrome, but I am no Pharma genious or Cytochrome expert.

As PT very rightly states depression of the CNS is always going to carry a risk. Age / weight/ Dosage / LFT's are all things to be taken into account.

If you have no tolerance for either product go much lower than what I use above. Way lower...

Always take caution, watch the dose and timings...

Peace and goodwill..

 

[HeirCroc1]

As @PTFC said, start low and see what happens. As a general matter, you should always google X interactions with Y before combining anything. Tramz have a potentially nasty interaction with a variety of drugs, though I think benz0s are okay.

 

[kinsona]

Yep, Tramzz and other opi8's or synthetic opii8's that bind to the same receptors could bring on Serotonin Syndrome. As @HeirCroc1 states. Google with multiple sources of information will corroborate and allow you to use wisely.

 

[HeirCroc1]

Also, Adderall lowers your seizure threshold and so do tramz. So there's that too. Definitely don't mix those two if you have a history of seizures.