I don't have real medical data for you gals/guys but 35mg oral became 60mg after 9 days daily use. Now I need to refresh every 4/5 hours.
Peak-times of 2/3 hours are still pleasurable and productive (if somewhat disorganized which is far better than doing nothing).
I can have small power-naps between refills, 30min half awake but still relaxing & refreshing, food intake 50% down, no antisocial side-effects (still married), rather friendly with people (NOT like some agro-pills), sexual drive increased but controllable, as opposed to the beloved old XTC (marriage?? LOL!!!). Sleep extra well at night, last dosage no later than 16.00. Seven h sleep and awake fresh to the first 60mg.
On a side-note: i'm far down on an op8 taper, so it's all relatively personal (always) but 2FA definitely helps me a ton to get through my work-days which were impossible drags before. When the op8 goes to zero (so help me God as planned in 6 weeks), I'll sure be on 100mg each pre-meal or switch to new research c.
Any questions welcome.