CL-218-872

bigjackchen

Member
VENDOR ACCOUNT
Joined
Jun 30, 2019
Messages
514
NEW PRODUCT:

CL-218,872:
IUPAC NAME: 3-methyl-6-[3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[3,4-f]pyridazine
CAS Number: 66548-69-4
Chemical formula: C13H9F3N4
Molar mass: 278.238 g•mol−1



CL-218,872 is a sedative and hypnotic drug used in scientific research.It has similar effects to sedative-hypnotic benzodiazepine drugs such as triazolam, but is structurally distinct and so is classed as a nonbenzodiazepine hypnotic.

CL-218,872 is a GABAA partial agonist which is selective for the α1 subtype.[3][4][5] It has a range of effects including sedative, hypnotic, anxiolytic, anticonvulsant and amnestic actions, however the most prominent actions are sedation and amnesia, and CL-218,872 produces effects very similar to those of the hypnotic imidazopyridine derivative zolpidem in animal studies.
This product is intended for laboratory research purposes only and are not to be used for any other purposes.
 
It’s partial agonist across the 1-6 or just the 5 mainstream subunits? Also, partial at GABAAR1 subunit or it has more traditional affinity comparable to a-drugs? any antagonistic action that could boot out full agonist like diazepam but not be itself able to give effects at the subunit level, causing mucho distress if you’re a chronic full agonist user as if 2, 3 are outcompeting your Xanax but not producing the strong conformational and post synaptic molecular changes that bring that GABA in close for that anxiety relief - it’s gonna be just like a can of ambien-light that causes instant wash it and wd for that everyday user. Interesting and this is the way the research must go. Thanks!
 
It's like a zdrug hybrid personally I would stay away, Ive had my vendors offer it to me and I've said absolutely no thank you. I suggest you all do the same they label it as a benzo but it is not a benzo.
 
It's like a zdrug hybrid personally I would stay away, Ive had my vendors offer it to me and I've said absolutely no thank you. I suggest you all do the same they label it as a benzo but it is not a benzo.
why do you recommend so strongly against this class? i'm not familiar with the reason z drugs are undesirable other than, i think, vague recall about intense nightmares and occasional sleep-walking and delirium associated with ambien.
 
Drugbuyersguide Shoutbox
  1. cannedgoods @ cannedgoods: Good day brothers! Hope yall are all good! 4MMC promo on my thread. US to US local delivery! Cheers!
  2. L @ Layne_Cobain: @Stevienixon cnc I believe
  3. T @ Tucker: Sorry @ dspring01, I just read your message wrong. No worries. 👍. Tried sending you a direct message but wouldn’t allow me. Maybe im at my limit, not sure. Good luck bud.
  4. D @ dspring01: @Tucker - I am sorry. What was your question?
  5. Stevienixon @ Stevienixon: Trying to find 7oh
  6. T @ Tucker: Hey @dspring01 what’s up with the sad looking face when asked where shipped too? Just asking
  7. F @ fyjclol: Scroll back & read it. Or read what he said on his thread.
  8. Saturnmeds @ Saturnmeds: What happened to calfresh? Someone stole his crypto?
  9. B @ bigblueallda: That sucks @CalFresh do you think it was an inside job? Or someone that knew.
  10. crimp @ crimp: do you live in a dangerous area maybe try moving to the country when you get back on your feet you seem to understant crypto beter then me so youll be on your feet in no time
  11. crimp @ crimp: do you live in a dangerous area maybe try moving to the country when you get back on your feet you seem to understant crypto beter then me so youll be on your feet in no time
  12. crimp @ crimp: glad youre good buddy
  13. CalFresh @ CalFresh: Thanks everyone. My family and I are safe ATM. @mellowella thank you, but they cleaned me out. the shelves are empty but I'm hoping to call in some favors to restock ASAP. @xenxra I will reach out to set up a secure comms channel for us. Thanks again all. Yesterday was tough, but the support I've received from those I can share is with has been a Godsend.
  14. tiquanunderwood @ tiquanunderwood: Mad love to you and your family @CalFresh
  15. xenxra @ xenxra: @CalFresh if you are able to DM me (in a secure manner) the transactions associated with your btc theft, i can look into that part for you at least. i;m still 99% certain if the fbi didn't discard my leads they could have gotten some of my coins back and considering you had your coins stolen within the us, you have a much better chance of recovery than me. unless they went through mixers i could probably trace them myself.
  16. O @ Outsider9173: @CalFresh Haven't been here long but I want to wish you a fast recovery
  17. crimp @ crimp: neck spine surgery 8 ribs broke and scalp split onen about 6 inches
  18. crimp @ crimp: need some help dude im so injured its not even funny dm me for details just need someone willing to help me fust for a week
  19. CnC5 @ CnC5: @CalFresh if theres anything i can do brother lmk!
  20. M @ Mokachin0: @CalFresh email me I may be able to assist
Back
Top