Wellbutrin and Tramadol, ok mix?

kyle4434

kyle4434

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Sep 3, 2013
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I have been on Wellbutrin for 4 months and it has helped me with energy and positivity so much... 

Anyways.. I want to get scripted  tramadol but I just saw someone say it shouldn't be mixed with Snris but I havent a clue.. if that's true is there another cheaper pain med one would recommend 

 
@kyle4434 My body dosnt do well with stimulants, Welbutirn , Adderall pretty much left me with life long restless leg syndrome and CNS pain that noly Gabapentin has helped me with. I had to make to switch over to Lexapro

 
Hi there. I have a little knowledge in this area. Maybe I can help.

There is at least 2 reasons that I know of why these 2 meds don’t mix.  The first, being the most prevalent is Serotonin syndrome.  Most anti-depressant meds like Wellbutrin  cause an uptake of serotonin being created in the body. Serotonin is a chemical produced to regulate mood and to stabilize the mood. 
Tramadol is one of the main pain meds (there are a few) that can also be used as mood stabilizers or as pain meds. It can change the way your brain receives pain.  And can cause an uptake in serotonin. So these 2 together causes this risk to rise. Serotonin syndrome can be dangerous. Please google.

Second reason that these 2 meds don’t mix well is because they both can lower the seizure threshold.  Wellbutrin alone has been known to cause seizures in people who have seizure disorders or even in those who don’t.

Since Tramodol has ssri properties to it among other things, it has also caused seizures. So these 2 together may be dangerous. Some people can and take them safely and successfully together but it doesn’t come without some risk.

 
@kyle4434 To add to this is would HIGHLY recommend getting the ‘Epocrates’ app on your cellphone.  It will tell you all possible interactions for whichever drugs you input.  It’s an amazing app!  

 
@kyle4434 CONTRAVE is a drug with Naltrexone/Bupropion ER (aka Wellbutrin).

It's used as a weight loss drug.  My point here is that it's MAYBE possible Wellbutrin can be mixed with other things too, but maybe start by reading about CONTRAVE and you'll learn about some of the interactions https://contrave.com/how-contrave-works/

P.S. I swear I'm an Engineer and NOT a pharmaceutical rep for Naltrexone, LOL.

 
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