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jewy do you know what strength they were taking? I see the mex vendors offer it in 100mcg, my source tells me he may have 25mcg soon... obviously a lower dose would be a better place to start just curious if that's low enough. I know you're not a doctor just wanted to reference it against your second hand knowledge from teammates experiences

 
Anytime my friend, anytime.
Yeah especially when people decide to chew them. It's 3 days worth of PK that you are swallowing  (hopefully bit by bit) that's 80 times stronger than Morfeen. People OD because the chew some and don't feel it, then chew more. It can take 45 minutes to feel it. I knew a girl in college who started the  class fine and then slumped over half way through. She had decided to chew on her 50 µg patch in class and went to the hospital.

 
Here RickJames, This will clue you in.

I believe I have already taken care of this for you via PM
smile.png
BUT... since it took me a minute to type up, I would be more than glad to share it with the board in hopes of helping someone out in educating one before they take the plunge to narcotic pain meds (Opiates/opioids)...

"FIRSTLY, PLEASE KNOW THAT I AM NOT A DOCTOR, NOR CLAIM TO BE ONE, I AM JUST AN ENTHUSIAST WHO HAPPENS TO HAVE A LOT OF PASSION FOR THE SUBJECTS OF: PHARMACOLOGY/PHARMICOKINETICS & PHARMICODYNAMICS! I also take harm reduction very seriously too! This post is meant to be informative reading and NOTHING ELSE! PLEASE SPEAK WITH YOUR PAIN MANAGEMENT DOCTOR IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT YOUR OWN PAIN MANAGEMENT PLAN!

Please allow me start by explaining the difference between opiates and opioids. These words are very often used interchangeably by many, not knowing what they truly mean; so before I start this "ESSAY" lol, I will start by helping to clear the air and define to everyone exactly what the difference between an opiate and an opioid is... An opiate, is a naturally occurring pain medication made/manufactured directly from the Opium Poppy (Papaver somniferum); by deriving and isolating very particular (And naturally occurring) alkaloids (Such as Codeine, Morphine, Thebaine, etc.) and using them directly without much more (If any at all) chemical manipulation. Examples of opiates are: Codeine (Tylenol #3, Paramol) and Morphine (Avinza, MS Contin). An opioid, is NOT naturally occurring and is either fully synthetic OR semi-synthetic. A semi-synthetic opioid, is one that starts life as [an] isolated alkaloid(s) from the Opium Poppy, very similar to opiates, however this is where the similarities stop. From there, after the wanted alkaloid(s) are extracted, the structure of said alkaloid(s) is then changed in such a way that the chemical chain is now altered and is considered "chemically different" than it's predecessor, creating a new substance that is part derived from a naturally occurring plant and part man-made/chemically altered by man. Examples of semi-synthetic opioids would be: Hydrocodone (Lortab, Vicodin), Oxycodone (Percocet, OxyContin) and Buprenorphine (Suboxone, Subutex). Fully synthetic opioids, are just that... FULLY synthetic. Meaning they do not start life as part of the Opium Poppy (Or one of it's alkoloids), it is actually made by man, with very specific chemicals, in a very specific manner... from scratch. Examples of FULLY synthetic opioids are: Methadone (Dolophine, Methadose), Pentazocine (Talwin, Fortwin) and Fentanyl (Sublimaze, Durogesic).

Now, with that out of the way... With this post, I am not only trying to help educate those who wish to learn a bit more on this topic, but I am also saying that the opiate naive (Individuals who are either new to pain meds or on other weaker opiates/opioids that seem to be helping control your pain fine [such as Codeine (Tylenol #3 and #4), Dihydrocodeine (Paracodin, Contugesic), [Dextro]Propoxyphene (Darvon, Darvocet), Hydrocodone (Vicodin, Lortab), etc.] should stay far away from these opiods like: METHADONE, OPANA AND ESPECIALLY FENTANYL! With that said...

Opana and Fentanyl have EXTREMELY short half lives/durations of action. The reason I say to stay away from them (Even though one will do what they want) is, when snorting drugs (I am not accusing anyone on this forum of doing so, but let's be real here, statistics do show, [and this can be Googled] that over half of all patients who are prescribed narcotics for pain or otherwise, will at some point and time try to do this/abuse their medication, if just once and never again, some times that is all it takes one to get hooked and/or overdose) and comparing Opana to Oxycodone (Via insufflation/snorted nasally), it (Opana) is easily up to 5 TIMES STRONGER THAN OXYCODONE, when compared MG to MG!

However, Opana's pain relieving properties (When abused/snorted) will only last about 1-2 hours (A significantly shorter period of time when compared to taking orally AKA as prescribed). This makes the want/need and urge to re-dose frequently in order to try and control the breakthrough pain one would experience when the analgesic effects of the dose rapidly disappear much sooner than expected; which in this day and age IS A REALITY!

And It is this compulsion that is JUST ONE of the MAJOR CONTRIBUTING FACTORS in CAUSING DEPENDENCE and/or TRIGGERING ADDICTION.

I am not going to up-talk the euphoria and pain killing properties because this drug is ALMOST as DANGEROUS as Fentanyl and can easily kill someone, not well tolerant to opiates, with a single 40mg pill! However, when taken orally, Opana works as an ER (Extended Release pill) medication (Much like that of OxyContin).

When taken orally, and swallowed whole (As directed/prescribed) Opana ER is said to last anywhere from 6-12 hours. If ONE were to EVER try this medication (And hopefully long down the road when not much else is helping, if at all), please only try the lowest dose possible, swallowed whole to see how you tolerate them.. and even swallowed, they are up to 2-3x as strong as Oxycodone! So please keep this in mind!

Fentanyl, I am not going to say to much about this drug, except for there is a good reason why it is usually only used/saved for cancer patients in stage 4, near death. Unlike Oxycodone and other opioids/opiates, Fentanyl (And its analogues: Sufentanyl, Carfentanyl, etc.) are measured in MICRO-grams! Meaning 1 micorgram is 1/1000th of a milligram. 100 micrograms = 0.1 mg! That is how strong this drug is! It needs to be measured in micrograms! This drug also has a VERY SHORT half life/duration of action (About 1-2 hours) and, when prescribed, is usually in an internal pump that releases the medication every 2-3 hours, or in dermal patch form (Applied to the skin) that stays on to release very small amount of the medication over a 72 HOUR period. The [Fentanyl] lollipops and buccal [oral] tablets are especially dangerous, because they come in VERY LARGE AMOUNTS (Of up to 800mcg and 1600mcg doses) and are for immediate release, only prescribed for breakthrough pain almost exclusively for patients using other means of Fentanyl therapy to begin with.

In my book, there is absolutely no need for ANYONE to touch this drug at all, unless they are on their death bed and NEED to be comfortable... PERIOD. Too many people have died from trying this drug and I do not want to see the same happen to any of you!

Now Methadone, while very long acting (And these days almost EXCLUSIVELY KNOWN for it's use in opioid replacement therapy for recovering addicts in treatment), has almost no recreational value, again, not assuming anyone here is using drugs for recreation, however (Still talking in terms of recreational value), this also means, in terms of euphoria, there is practically none. It won't give you any type of energy that Oxycodone MAY (Which some people describe experiencing as a side effect, some don't); in fact it (Methadone) may very well do the opposite and make you want to lay around and do nothing all day. Though, it is definitely worth mentioning, Methadone does a very good job at what it was initially created for, pain relief (Which is what we are talking about in this post, trying to stay on topic here
smile.png
). The half life is about 28-32 hours, making once daily (Or some times twice daily, depending on pain level) dosing very appropriate; however, I would not recommend this drug to anyone at all. If you become dependent on it, IT WILL TAKE A GOOD 2 MONTHS OF WITHDRAWAL to come off! I know this first hand and I will never touch it again!

Besides the negative points listed already, again an opiate naive person needs only to take 30-40mg of this drug to OD and die. The LD/50 for the average male, I believe, is ONLY 50mg! I WOULD NOT GO NEAR THIS STUFF WITH A STICK!

However, it would be very biased for me not to state, that when used/prescribed the way it's supposed to be, it can be a very legitimate option for those suffering in pain! The only way to decide whether it would be right for you or not (As with any of the meds listed in this post), would be to sit down with your pain management doctor to discuss the options!

Now, as far as Oxycontin, I would actually recommend this OVER Roxicodone to anyone in pain (Who has tried other meds, which have unsuccessfully been able to subdue their pain in a controlled manner and/or at the same time, as a consequence, built a tolerance to such), now looking to start on something a bit stronger.

It (OxyContin) has gotten a lot of bad hype in the press over the years, but, where that has now been fixed, Roxicodone is NOW TAKING OVER (GETTING A BAD REP)! OxyContin stands for Oxycodone Continuous Release. The active ingredient is the exact same as in Roxicodone, Percocet, etc however, added into the pills during the manufacturing phase (Besides the binders/fillers already used to give the pill mass, shape and hold it together), is a time release agent... This is a wax-like substance/matrix that allows the pill to continuously disperse it's medication at a steady, continuous pace (Instead of just instantaneously like other formulations) while still in your stomach being digested/processed throughout the day.

These pills are actually very safe when taken as directed and swallowed whole. For a pain treatment plan (That is discussed with your pain management doctor), to help control pain all day (When all else fails), I would highly recommend asking about more info on OxyContin with your doctor; since in most cases, all one needs is a single pill/dose in the morning, while perhaps still using another form (I.R. or instant release) of pain relief/medication for any breakthrough pain that one may (Or may not) experience throughout the day.

If pain isn't held back and controlled well enough by this regimen, you could add another OxyContin pill, 8-12 hours later, to help subdue/relieve any pain one may (Or may not) experience throughout the night (If you have trouble sleeping through it or have problems with your pain waking you up in the middle of the night), still perhaps using another form of instant release pain medication to help combat breakthrough pain, if/as needed.

Now here is the kicker... because OxyContin was abused (And publicly scrutinized) for so long, the manufacturer (Purdue Pharma) was under quite a bit of pressure over the years to make a more "abuse-proof" formulation of their popular and "over-prescribed" narcotic (OxyContin). Since in the past, it was very, very easy to defeat the time-release mechanism in the pills, causing it to release very HIGH amounts of Oxycodone (Designed to be released slowly and continuously throughout the entire day) instantly! Which of course resulted in many, many deaths and overdoses (And resulting lawsuits) that were blamed on the flaws of the manufacturer's "continuous release" feature. So now, Purdue Pharma, has recently (Within the past few years now) reformulated this pill.

So now, instead of the pills being imprinted with "OC", they are marked with an "OP" to indicate such (New formulation). These have not been accepted well by patients! Don't get me wrong, they do work for some (Maybe even for some of you!), but for most, the new formula is a failure! The pills are now basically MADE OUT OF A PLASTIC-TYPE MATERIAL, making them nearly uncrushable! And while this does help detour "would-be abusers" from doing so, it has been at the cost of helping people with their pain.

There have been reports that the (Newly formulated, "OP" OxyContin) pills do not get fully broken down (Before it is completely digested) in the stomach (In part, mainly because of the chemicals/compounds used in the new formulation), wasting some of, if not MOST of the medicine in the pill. Again, don't get me wrong here, there are no professional reports/trials (To my knowledge) to prove this, and it could be all false... Hey, they could work for you! However, should you be prescribed OxyContin as part of your pain management plan, if possible, ask the pharmacist (When dropping off the prescription to be filled) if the "OC" version of OxyContin (The original formula) is one that they have in stock/carry and would be able to use to fill your script. As these are said to and have been reported by many to work much better and more reliably at controlling pain (Than the new "OP" formula).

The only issue here is... they have been out of production FOR QUITE A WHILE NOW! So chances are, if the pharmacy says they do have some, you would have to believe they are either left over stock (Which will indeed be COMPLETELY GONE by this year's end, if not already) and/or are past their expiration date (Though I have taken many prescribed drugs up to a few years past their expiry date only to find they work just fine still). If, however (And this is more likely to be the case), the pharmacy says they do not have any of these in stock, your next best bet would be to see if they have the brand ABG (Ivax Pharmaceuticals) generic version of the medication. To my knowledge, this is still the old formula as well, and may (Or may not) work best for you!

Lastly, Morphine. This could be another helpful med for one to use to control pain. They come in both immediate release and sustained or continuous release formulations. Morphine Sulfate SR (Or sustained release) or MSContin (Also manufactured by Purdue Pharma, the same company that makes OxyContin). They are about the same size as OxyContin pills, except for the higher dosed formulations (Such as 100mg & 120mg) obviously have the number 100 or 120 on them and they are different in color (Than the color scheme to indicate dosage used for OxyContin pills).

Morphine is known to be a little less potent than Oxycodone (About 1/2 - 1/3 less strong, milligram for milligram) and the same type of release mechanism/formulation is used in the sustained/continuous release versions of the pill as is used in the OxyContin formula to control the release of pain killing analgesic over the course of an extended period of time (Also approximately said to last 8-12 hrs.). One drawback from Morphine, however, is it's very low ORAL bioavailability. It can be researched, but from my findings, I have seen an average range of 15-20%, which, when compared to Oxycodone's ORAL bioavailability of 50-60% is really not that much (Which is also why higher doses of oral Morphine therapy are usually needed to control pain efficiently, when compared to Oxycodone)!

Usually doctors will try patients out on an oral form of Morphine before advancing to Oxycodone, because it (Morphine) is quite often considered less potent (If an identical dose of each is compared side by side, mg for mg). This is not only because of it's lower oral bioavailability, but also from an analgesic/pain killing perspective as well. Just because they may (Or may not) work for you, regardless of what I said above, they do work for A LOT of people; and you should not discredit them (Unless you have tried them unsuccessfully at a previous time).

With all of this in mind, and what you are taking seems to be helping you already (And managing your pain as well as you'd like), I do not want to dissuade you from continuing down your current path, but if there is even a shadow of a doubt, and you think your pain could indeed be controlled more effectively/efficiently, it may be worth at least your time to go in and talk to your doctor about it! Let me know if you have any more questions!

Either way, please be safe and be careful! AND REMEMBER, I AM NOT A DOCTOR, NOR CLAIM TO BE ONE, I AM JUST AN ENTHUSIAST WHO HAPPENS TO HAVE A LOT OF PASSION FOR THE SUBJECTS OF: PHARMACOLOGY/PHARMICOKINETICS & PHARMICODYNAMICS! I also take harm reduction very seriously too! This post is meant to be informative reading and NOTHING ELSE! PLEASE SPEAK WITH YOUR PAIN MANAGEMENT DOCTOR IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT YOUR OWN PAIN MANAGEMENT PLAN!

Please take everything I say with a grain of salt and of course there are many other forums out there about drug information I would suggest you would try to Google to get yourself educated before talking about (With your doctor) or starting ANYTHING NEW AT ALL!"

But if anyone does have any more questions that I may be able to help with, please feel free to ask! That's what we're here for! Have a great night everyone!

Take care and be safe!

Provided by ACE

Wow, you know your stuff. Really good info. Thanks a lot

 
Wow, you know your stuff. Really good info. Thanks a lot
In my opinion, a bit of an understatement, but I know I often have difficulty putting into words how thankful I am that others are such gracious geniuses, willing to share their knowledge with anyone they think could benefit.

Rick, I am not trying to give you a hard time, that was a SIGNIFICANT amount information posted on not just your behalf but for so many others (myself included).

I am in general awe much of the time as I read this board...and it can be difficult to convey true appreciation via text.

Seems I have been a party to keeping his forum off topic a bit...I'll stop now and hope the best for you Rick and so many others who Young's posts have certainly enlightened.

Take Care

 
In my opinion, a bit of an understatement, but I know I often have difficulty putting into words how thankful I am that others are such gracious geniuses, willing to share their knowledge with anyone they think could benefit.

Rick, I am not trying to give you a hard time, that was a SIGNIFICANT amount information posted on not just your behalf but for so many others (myself included).

I am in general awe much of the time as I read this board...and it can be difficult to convey true appreciation via text.

Seems I have been a party to keeping his forum off topic a bit...I'll stop now and hope the best for you Rick and so many others who Young's posts have certainly enlightened.

Take Care
I have to agree with you here, Beranda...

I have learned so much from this forum - the information compiled here is endless.  I feel as if I am educated with something new every single day - and by people that are willing lead us with this information as long as we are just willing to take the time to read it.  A very small price to pay.  Why would anyone want a quick answer, someone to just tell them how to navigate around this system quickly - when they can read about, learn every aspect and not have to flip out when you don't know what is going on?  Knowledge is priceless.

 
Hey everyone.

I've been out of this game for about 6 months now.

Has J's email changed in this time, is there anything that needs to be aware of that's changed?

Is there still a problem with "Pin Man" stricking once per month. The guy that slits the envelopes, takes out the goods, and sends you pins.

 
Last edited by a moderator:
Here RickJames, This will clue you in.

I believe I have already taken care of this for you via PM
smile.png
BUT... since it took me a minute to type up, I would be more than glad to share it with the board in hopes of helping someone out in educating one before they take the plunge to narcotic pain meds (Opiates/opioids)...

"FIRSTLY, PLEASE KNOW THAT I AM NOT A DOCTOR, NOR CLAIM TO BE ONE, I AM JUST AN ENTHUSIAST WHO HAPPENS TO HAVE A LOT OF PASSION FOR THE SUBJECTS OF: PHARMACOLOGY/PHARMICOKINETICS & PHARMICODYNAMICS! I also take harm reduction very seriously too! This post is meant to be informative reading and NOTHING ELSE! PLEASE SPEAK WITH YOUR PAIN MANAGEMENT DOCTOR IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT YOUR OWN PAIN MANAGEMENT PLAN!

Please allow me start by explaining the difference between opiates and opioids. These words are very often used interchangeably by many, not knowing what they truly mean; so before I start this "ESSAY" lol, I will start by helping to clear the air and define to everyone exactly what the difference between an opiate and an opioid is... An opiate, is a naturally occurring pain medication made/manufactured directly from the Opium Poppy (Papaver somniferum); by deriving and isolating very particular (And naturally occurring) alkaloids (Such as Codeine, Morphine, Thebaine, etc.) and using them directly without much more (If any at all) chemical manipulation. Examples of opiates are: Codeine (Tylenol #3, Paramol) and Morphine (Avinza, MS Contin). An opioid, is NOT naturally occurring and is either fully synthetic OR semi-synthetic. A semi-synthetic opioid, is one that starts life as [an] isolated alkaloid(s) from the Opium Poppy, very similar to opiates, however this is where the similarities stop. From there, after the wanted alkaloid(s) are extracted, the structure of said alkaloid(s) is then changed in such a way that the chemical chain is now altered and is considered "chemically different" than it's predecessor, creating a new substance that is part derived from a naturally occurring plant and part man-made/chemically altered by man. Examples of semi-synthetic opioids would be: Hydrocodone (Lortab, Vicodin), Oxycodone (Percocet, OxyContin) and Buprenorphine (Suboxone, Subutex). Fully synthetic opioids, are just that... FULLY synthetic. Meaning they do not start life as part of the Opium Poppy (Or one of it's alkoloids), it is actually made by man, with very specific chemicals, in a very specific manner... from scratch. Examples of FULLY synthetic opioids are: Methadone (Dolophine, Methadose), Pentazocine (Talwin, Fortwin) and Fentanyl (Sublimaze, Durogesic).

Now, with that out of the way... With this post, I am not only trying to help educate those who wish to learn a bit more on this topic, but I am also saying that the opiate naive (Individuals who are either new to pain meds or on other weaker opiates/opioids that seem to be helping control your pain fine [such as Codeine (Tylenol #3 and #4), Dihydrocodeine (Paracodin, Contugesic), [Dextro]Propoxyphene (Darvon, Darvocet), Hydrocodone (Vicodin, Lortab), etc.] should stay far away from these opiods like: METHADONE, OPANA AND ESPECIALLY FENTANYL! With that said...

Opana and Fentanyl have EXTREMELY short half lives/durations of action. The reason I say to stay away from them (Even though one will do what they want) is, when snorting drugs (I am not accusing anyone on this forum of doing so, but let's be real here, statistics do show, [and this can be Googled] that over half of all patients who are prescribed narcotics for pain or otherwise, will at some point and time try to do this/abuse their medication, if just once and never again, some times that is all it takes one to get hooked and/or overdose) and comparing Opana to Oxycodone (Via insufflation/snorted nasally), it (Opana) is easily up to 5 TIMES STRONGER THAN OXYCODONE, when compared MG to MG!

However, Opana's pain relieving properties (When abused/snorted) will only last about 1-2 hours (A significantly shorter period of time when compared to taking orally AKA as prescribed). This makes the want/need and urge to re-dose frequently in order to try and control the breakthrough pain one would experience when the analgesic effects of the dose rapidly disappear much sooner than expected; which in this day and age IS A REALITY!

And It is this compulsion that is JUST ONE of the MAJOR CONTRIBUTING FACTORS in CAUSING DEPENDENCE and/or TRIGGERING ADDICTION.

I am not going to up-talk the euphoria and pain killing properties because this drug is ALMOST as DANGEROUS as Fentanyl and can easily kill someone, not well tolerant to opiates, with a single 40mg pill! However, when taken orally, Opana works as an ER (Extended Release pill) medication (Much like that of OxyContin).

When taken orally, and swallowed whole (As directed/prescribed) Opana ER is said to last anywhere from 6-12 hours. If ONE were to EVER try this medication (And hopefully long down the road when not much else is helping, if at all), please only try the lowest dose possible, swallowed whole to see how you tolerate them.. and even swallowed, they are up to 2-3x as strong as Oxycodone! So please keep this in mind!

Fentanyl, I am not going to say to much about this drug, except for there is a good reason why it is usually only used/saved for cancer patients in stage 4, near death. Unlike Oxycodone and other opioids/opiates, Fentanyl (And its analogues: Sufentanyl, Carfentanyl, etc.) are measured in MICRO-grams! Meaning 1 micorgram is 1/1000th of a milligram. 100 micrograms = 0.1 mg! That is how strong this drug is! It needs to be measured in micrograms! This drug also has a VERY SHORT half life/duration of action (About 1-2 hours) and, when prescribed, is usually in an internal pump that releases the medication every 2-3 hours, or in dermal patch form (Applied to the skin) that stays on to release very small amount of the medication over a 72 HOUR period. The [Fentanyl] lollipops and buccal [oral] tablets are especially dangerous, because they come in VERY LARGE AMOUNTS (Of up to 800mcg and 1600mcg doses) and are for immediate release, only prescribed for breakthrough pain almost exclusively for patients using other means of Fentanyl therapy to begin with.

In my book, there is absolutely no need for ANYONE to touch this drug at all, unless they are on their death bed and NEED to be comfortable... PERIOD. Too many people have died from trying this drug and I do not want to see the same happen to any of you!

Now Methadone, while very long acting (And these days almost EXCLUSIVELY KNOWN for it's use in opioid replacement therapy for recovering addicts in treatment), has almost no recreational value, again, not assuming anyone here is using drugs for recreation, however (Still talking in terms of recreational value), this also means, in terms of euphoria, there is practically none. It won't give you any type of energy that Oxycodone MAY (Which some people describe experiencing as a side effect, some don't); in fact it (Methadone) may very well do the opposite and make you want to lay around and do nothing all day. Though, it is definitely worth mentioning, Methadone does a very good job at what it was initially created for, pain relief (Which is what we are talking about in this post, trying to stay on topic here
smile.png
). The half life is about 28-32 hours, making once daily (Or some times twice daily, depending on pain level) dosing very appropriate; however, I would not recommend this drug to anyone at all. If you become dependent on it, IT WILL TAKE A GOOD 2 MONTHS OF WITHDRAWAL to come off! I know this first hand and I will never touch it again!

Besides the negative points listed already, again an opiate naive person needs only to take 30-40mg of this drug to OD and die. The LD/50 for the average male, I believe, is ONLY 50mg! I WOULD NOT GO NEAR THIS STUFF WITH A STICK!

However, it would be very biased for me not to state, that when used/prescribed the way it's supposed to be, it can be a very legitimate option for those suffering in pain! The only way to decide whether it would be right for you or not (As with any of the meds listed in this post), would be to sit down with your pain management doctor to discuss the options!

Now, as far as Oxycontin, I would actually recommend this OVER Roxicodone to anyone in pain (Who has tried other meds, which have unsuccessfully been able to subdue their pain in a controlled manner and/or at the same time, as a consequence, built a tolerance to such), now looking to start on something a bit stronger.

It (OxyContin) has gotten a lot of bad hype in the press over the years, but, where that has now been fixed, Roxicodone is NOW TAKING OVER (GETTING A BAD REP)! OxyContin stands for Oxycodone Continuous Release. The active ingredient is the exact same as in Roxicodone, Percocet, etc however, added into the pills during the manufacturing phase (Besides the binders/fillers already used to give the pill mass, shape and hold it together), is a time release agent... This is a wax-like substance/matrix that allows the pill to continuously disperse it's medication at a steady, continuous pace (Instead of just instantaneously like other formulations) while still in your stomach being digested/processed throughout the day.

These pills are actually very safe when taken as directed and swallowed whole. For a pain treatment plan (That is discussed with your pain management doctor), to help control pain all day (When all else fails), I would highly recommend asking about more info on OxyContin with your doctor; since in most cases, all one needs is a single pill/dose in the morning, while perhaps still using another form (I.R. or instant release) of pain relief/medication for any breakthrough pain that one may (Or may not) experience throughout the day.

If pain isn't held back and controlled well enough by this regimen, you could add another OxyContin pill, 8-12 hours later, to help subdue/relieve any pain one may (Or may not) experience throughout the night (If you have trouble sleeping through it or have problems with your pain waking you up in the middle of the night), still perhaps using another form of instant release pain medication to help combat breakthrough pain, if/as needed.

Now here is the kicker... because OxyContin was abused (And publicly scrutinized) for so long, the manufacturer (Purdue Pharma) was under quite a bit of pressure over the years to make a more "abuse-proof" formulation of their popular and "over-prescribed" narcotic (OxyContin). Since in the past, it was very, very easy to defeat the time-release mechanism in the pills, causing it to release very HIGH amounts of Oxycodone (Designed to be released slowly and continuously throughout the entire day) instantly! Which of course resulted in many, many deaths and overdoses (And resulting lawsuits) that were blamed on the flaws of the manufacturer's "continuous release" feature. So now, Purdue Pharma, has recently (Within the past few years now) reformulated this pill.

So now, instead of the pills being imprinted with "OC", they are marked with an "OP" to indicate such (New formulation). These have not been accepted well by patients! Don't get me wrong, they do work for some (Maybe even for some of you!), but for most, the new formula is a failure! The pills are now basically MADE OUT OF A PLASTIC-TYPE MATERIAL, making them nearly uncrushable! And while this does help detour "would-be abusers" from doing so, it has been at the cost of helping people with their pain.

There have been reports that the (Newly formulated, "OP" OxyContin) pills do not get fully broken down (Before it is completely digested) in the stomach (In part, mainly because of the chemicals/compounds used in the new formulation), wasting some of, if not MOST of the medicine in the pill. Again, don't get me wrong here, there are no professional reports/trials (To my knowledge) to prove this, and it could be all false... Hey, they could work for you! However, should you be prescribed OxyContin as part of your pain management plan, if possible, ask the pharmacist (When dropping off the prescription to be filled) if the "OC" version of OxyContin (The original formula) is one that they have in stock/carry and would be able to use to fill your script. As these are said to and have been reported by many to work much better and more reliably at controlling pain (Than the new "OP" formula).

The only issue here is... they have been out of production FOR QUITE A WHILE NOW! So chances are, if the pharmacy says they do have some, you would have to believe they are either left over stock (Which will indeed be COMPLETELY GONE by this year's end, if not already) and/or are past their expiration date (Though I have taken many prescribed drugs up to a few years past their expiry date only to find they work just fine still). If, however (And this is more likely to be the case), the pharmacy says they do not have any of these in stock, your next best bet would be to see if they have the brand ABG (Ivax Pharmaceuticals) generic version of the medication. To my knowledge, this is still the old formula as well, and may (Or may not) work best for you!

Lastly, Morphine. This could be another helpful med for one to use to control pain. They come in both immediate release and sustained or continuous release formulations. Morphine Sulfate SR (Or sustained release) or MSContin (Also manufactured by Purdue Pharma, the same company that makes OxyContin). They are about the same size as OxyContin pills, except for the higher dosed formulations (Such as 100mg & 120mg) obviously have the number 100 or 120 on them and they are different in color (Than the color scheme to indicate dosage used for OxyContin pills).

Morphine is known to be a little less potent than Oxycodone (About 1/2 - 1/3 less strong, milligram for milligram) and the same type of release mechanism/formulation is used in the sustained/continuous release versions of the pill as is used in the OxyContin formula to control the release of pain killing analgesic over the course of an extended period of time (Also approximately said to last 8-12 hrs.). One drawback from Morphine, however, is it's very low ORAL bioavailability. It can be researched, but from my findings, I have seen an average range of 15-20%, which, when compared to Oxycodone's ORAL bioavailability of 50-60% is really not that much (Which is also why higher doses of oral Morphine therapy are usually needed to control pain efficiently, when compared to Oxycodone)!

Usually doctors will try patients out on an oral form of Morphine before advancing to Oxycodone, because it (Morphine) is quite often considered less potent (If an identical dose of each is compared side by side, mg for mg). This is not only because of it's lower oral bioavailability, but also from an analgesic/pain killing perspective as well. Just because they may (Or may not) work for you, regardless of what I said above, they do work for A LOT of people; and you should not discredit them (Unless you have tried them unsuccessfully at a previous time).

With all of this in mind, and what you are taking seems to be helping you already (And managing your pain as well as you'd like), I do not want to dissuade you from continuing down your current path, but if there is even a shadow of a doubt, and you think your pain could indeed be controlled more effectively/efficiently, it may be worth at least your time to go in and talk to your doctor about it! Let me know if you have any more questions!

Either way, please be safe and be careful! AND REMEMBER, I AM NOT A DOCTOR, NOR CLAIM TO BE ONE, I AM JUST AN ENTHUSIAST WHO HAPPENS TO HAVE A LOT OF PASSION FOR THE SUBJECTS OF: PHARMACOLOGY/PHARMICOKINETICS & PHARMICODYNAMICS! I also take harm reduction very seriously too! This post is meant to be informative reading and NOTHING ELSE! PLEASE SPEAK WITH YOUR PAIN MANAGEMENT DOCTOR IF YOU HAVE ANY QUESTIONS OR CONCERNS ABOUT YOUR OWN PAIN MANAGEMENT PLAN!

Please take everything I say with a grain of salt and of course there are many other forums out there about drug information I would suggest you would try to Google to get yourself educated before talking about (With your doctor) or starting ANYTHING NEW AT ALL!"

But if anyone does have any more questions that I may be able to help with, please feel free to ask! That's what we're here for! Have a great night everyone!

Take care and be safe!

Provided by ACE
Stop lying...you are the Love Dr.

 
Placed order: 8/26

TN: 8/27

Received: 8/29

I'm choking up...I never thought this day would come...J is the man! sniffle sniffle

 
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So far J has been an absolute pleasure to deal with. Placed an order on day 1, received TN that night and out for delivery on day 2.

 
Buddychrist** said:
Great info on the previous posts regarding treating some of these products with extreme caution. I personally would not order anything that I have not had a Dr RX to me previously or understand what it is, strength and proper dosage. A product that can kill you with one miss used dose? That's scary.
That's good because you're right that when it comes to any medication, you should talk to a doctor, pharmacist, or do extensive research on your own. A person's physiology is different than someone else's and one person may react adversely to the next person whether it be strong pain medications or even just simple acetaminophen or ibuprofen.

Even if a doc prescribes an RX, I personally do as much research as possible in how it can affect oneself. I have been prescribed many meds for depression, anxiety, etc., and I try to go into the Doctor's office already having knowledge of the meds I believe they are going to try to prescribe me.

 
Was I the fool of the month?  J took my order, took my money, and sent me an empty envelope.  What a first experience.

 
If any of you have some sort of "special" relationship with J - maybe put a bug in his ear that this is not cool at all.  I sent my money in good faith - based in part on what I have read here.  I know it's still a game of chance, but..... c'mon.

 
If any of you have some sort of "special" relationship with J - maybe put a bug in his ear that this is not cool at all.  I sent my money in good faith - based in part on what I have read here.  I know it's still a game of chance, but..... c'mon.
99 has, to my knowledge, the closest relationship with J among our membership, although unfortunately, he's somewhat indisposed at the moment attending to some personal matters. He did check in over the past few days, so hopefully he will do so again this weekend and get in touch with you and / or J if he is able. Otherwise, I'm sure that there are others who might be able to communicate with J regarding your situation.

 
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  1. LatsDoodis @ LatsDoodis: @SeaDonkey I think everyone deserves a second chance. I worked all night so eclipsing my life away… I do love stargazing and a telescope is high on my list of things to do when I’m high!
  2. iamgroot @ iamgroot: replied you already
  3. iamgroot @ iamgroot: are you talking about me? lol
  4. Diz-E @ Diz-E: @ I am Groot--I emailed ya bro, Diz-E
  5. SeaDonkey @ SeaDonkey: @LatsDoodis by tonight I meant like 16 hours from now, so you still have a chance!
  6. LatsDoodis @ LatsDoodis: @SeaDonkey ooh, I just got home, too, but Iit was raining here all of a sudden! How was it?
  7. SeaDonkey @ SeaDonkey: Anyone else gonna watch the lunar eclipse tonight
  8. S @ scarred14: @RussianRambo who did?
  9. xenxra @ xenxra: what the fudge
  10. R @ RussianRambo: he set up a controlled delivery on 2 people
  11. R @ RussianRambo: Slaughter AKA Slaughterhouse is no good anymore
  12. R @ RussianRambo: coolchems no good
  13. hiTillidie @ hiTillidie: Just yankin your lobe jason...once paid you should have privleges.
  14. hiTillidie @ hiTillidie: You gotta buy vendor coupons first...
  15. J @ jason1974: How do i access approved vendors now that i am a member?
  16. xenxra @ xenxra: @jason1974 every single time someone pops up with that handle, they're a scammer. my browser gives me a security warning for their site.
  17. hiTillidie @ hiTillidie: Coolchems is no good
  18. hiTillidie @ hiTillidie: Xenxra yeah fir sure.pigpredictable
  19. J @ jason1974: Can anybody vouch for Coolchems.com?
  20. J @ jason1974: Can anybody vouch for Coolchems.com?
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