There seems to be a lot of different questions and concerns regarding Kratom use and I'd like to share my limited knowledge in the off chance it helps someone. This is one of my first posts, so please pardon me if I break any rules or do not follow common forum décor. I know the basic physiological actions of Kratom but I am by no means an expert, so my knowledge of Kratom is mostly based off personal experience(s). An important aspect of Kratom that people should understand is that there is a huge amount of variability between differing strands sold by vendors. For instance a Kratom type such as "Red Vein Thai" may have significantly different effects depending on your source.
Because of the vast differences in Kratom quality and strength it is vital to only use trusted vendors that provide honest advertising on their products. Since it is relatively new to America it is often sold by inexperienced vendors or shady vendors that may send you an unknown strand with unknown strength. Bad vendors tend to make up their own strand names and over hype the substance as a "legal high" or as the "newest painkiller". Under no circumstance should you ever purchase Kratom from a head shop. They tend to sell mislabeled Kratom blends in capsules, and it will assuredly be way overpriced and of questionable quality. The quality of your Kratom experience will be a night and day difference depending on who your vendor is. Do your own research to find quality vendors, with a good place to start being right here. Good vendors tend to have some level of consistency in their products so you can experiment to find a strain that offers the effects you are looking for.
The strains of Kratom can be confusing and misleading if you don't have a little personal experience to gauge what you like and dislike. There are certain common strains such as Bali, Indonesian, Malaysian, Borneo and Thai. Even within these strains there is still a lot of difference in effects depending on the batch you get, which is why it is vital to find a reputable vendor. Strains are typically broken down into the vein colors such as red, green and white. To get a good grasp on which strand is right for you it is going to take some time spent in research and in personal trial and error. In general, red veins tend to be more sedating and analgesic, while green and white veins tend to be more stimulating. I have tried just about all strands from multiple vendors, and I have repeatedly found Bali to be the most enjoyable and consistent strain. There simply is not a best strain, as it is dependent on your preferences. My advice to new users is to purchase a variety pack to determine how you react to different types.
When first starting, just like all other substances, you should start in small doses. Inexperienced users should start with an amount as small as a gram in order to make sure you do not react adversely to it. Small doses tend to be stimulating and energetic, while higher doses may become sedating. Kratom should not be treated like your common prescription opiate. The mentality of "more is better" will end poorly with Kratom, and I have seen this happen repeatedly for my friends. Too high of doses usually results in extreme nausea, vertigo, irritability and a blazing head ache. Slowly experiment to find your preferred dose, and quit dosing when you begin to feel any adverse effects. People like to compare Kratom to opiates because of the mu-opiod reaction, but it does not behave identically and thus you should not expect identical results. The effects of Kratom are significantly different from opiates, and the experience you have will differ greatly depending on how much you take.
The exact reaction you have to Kratom varies drastically but is usually subtle. It is commonly used to combat pain or as a mild mood lift. The first time I took Kratom it was highly stimulating and energetic. After it kicked in I got a great run in and afterwards spent an enjoyable evening with my friends. It was a noticeable mental difference from baseline, but in comparison to other commonly used substances it was much less pronounced. One of the most common reasons people take Kratom is pain relief, or to taper off prescription pain medications with less WDs (or none). I do not have personal experience using Kratom to taper off opiates, but it seems to be relatively successful if you carefully manage your doses. However, it is easy to swap one addiction for another. Granted, a Kratom addiction is probably preferred to most other addictions, but is still a serious issue.
When I was first introduced to Kratom I was told that there was no risk of dependence and that it was fine to use regularly. I have found this (as have others) to be false and dangerously misleading. The rise in tolerance and risk of dependence is clearly more mild then most common opiates it is compared to, but if used too regularly there is absolutely risk for addiction. Kratom withdrawals are somewhat similar to opiate withdrawals and you will get the restless legs, irritability, sleepless nights, etc.. I have yet to see someone struggle with Kratom addiction in the same manner as other medications, but this substance should still be taken with the knowledge that it can cause dependence. To avoid getting a physical dependence try to space out dosing and create a concrete limit for yourself. When you begin to take it too regularly you will definitely begin to lose the positive effects it has. The initial effects can make it tempting to continue using it frequently, but I have found myself at times taking large quantities with no positive effects. As I said before, you can't just keep upping the dose to get the reaction you would like. There is a certain maximum positive dosage for most people and exceeding it almost always leads to negative side effects. All you can do once you lose the positive reaction is to reduce tolerance or find a differing strain to change it up.