Edit: Wow, this got way long. Maybe I should've started my own thread, especially since the Effexor might be useful information for someone some day? I can't find anyone else on the Internet who's made the same discovery and actually tried it.
Came to the forum with the same problem.
I'm getting myself off of Tramadol after 3 years of on-and-off again use. Made some bad decisions while on the drug and pushed away some friends to take pills instead. Seemed like a good idea at the time. Now I'm in a position where I've got to fix some things, but first I have to get off of the drug.
I got up to 16 of the 50mg pills a day to get a pleasant feeling, a feeling that of course lasts nowhere as long as it used to. Occasionally spiked up to 20 or 24 in a day.
Today is day five of the quitting process.
Sunday I took my last "real" dose of Tramadol, 10 pills, IIRC. I got myself through my Monday at work, bracing myself for when they would inevitably start to wear off. This started happening in the early afternoon when all the usual symptoms of both opiate and SSRI/SNRI withdrawl crept up. Driving myself home from work was incredibly difficult. Monday night in bed was a sweat-soaked hell.
Tuesday morning I was in full withdrawl. Body hurt like hell, full body restlessness, no position comfortable for a few seconds, exhausted but sleepless. An additional bizarre physical symptom: Muscles don't want to relax after being tensed. Every big yawn or stretch results in a body that I have to will to go slack again. Then their were the "brain zaps" and dizziness effects of the SSRI/SNRI withdrawl as well, now in full maximum strength. Profound depression and dark thoughts.
Aaahhh... but I had a secret weapon to try. I had picked up some Venlafaxine (Effexor), 50mg pills, after reading over and over again (as many of you probably have too) about high similarity between it and Tramadol. Some sources say that Effexor is effectively Tramadol engineered to remove the opiate effects, so the obvious idea is to make Tramadol withdrawl easier by delaying the worst half of it, in my opinion: the SSRI/SNRI withdrawl.
I can report that it is doing the job, and very well for me, too. Once I switched over, I did not have to endure brain zaps and dizziness at all, nor the full brunt of the other SSRI/SNRI withdrawl symptoms. Some depression remained, but a portion of that can also be blamed on the opiate withdrawl, and it has not nearly gotten down to the extreme depths I got into the last times (plural) I tried to get off this.
To switch from the two, on Tuesday morning I took 1 Tramadol and 3 (150mg total) Effexor. Very soon the SSRI/SNRI withdrawl symptoms went away as described above. The remaining opiate withdrawl side effects were still there and were still unholy. It was a miserable day on the couch shivering to the point of tremors while still burning alive. Napped in short, feverish fits. Took 100mg Effexor again in the evening. Took a Beandryl and suffered through a hellish sweat-soaked night again with little real sleep.
Wednesday morning, still no SSRI/SNRI withdrawl effects. Take 100mg Effexor and return to couch to continue the suffering. I know from years of listening to Loveline that Dr. Drew says that opiate withdrawl is "5 days of hell and done", which is maybe a little optimistic, but matches many timelines I see online. So I just keep accepting the suffering--until I realized I'd eaten the last of the "real" food in the house and I'd need to go to the store if I don't want to feed myself garbage through the rest of this.
I saw this next step a necessary evil. I took 2 of my 5 remaining Tramadol to get myself into some kind of functional physical state, go the store (stopping and resting many times), and get the hell home. The bad news is that I was so proud of myself that I got weak and take two more Tramadol /default_sad.png with no real meaningful effect except to make me regret wasting them.
Because of the 4 Tramadol I took, I did not take any Effexor on Wednesday night. That night I resolved to at least take advantage of my weakness by getting some sleep, which was not great, but was slightly better than the previous two nights. Still frequent awakenings, but I stayed in bed two hours longer into the morning than I did on other nights.
Thursday, yesterday, 100mg Effexor in the morning. History Channel and fitful naps on the couch all day. I took my last one remaining Tramadol in the middle of the day to taper from the four I'd had yesterday. 100mg Effexor in the evening. NyQuil at bed time to try to get more sleep. Sleep perhaps barely a little better in quality, but I couldn't get myself back to sleep very well after light started coming through the windows in the morning.
Today is Friday, day 5. Wake up with light SSRI/SNRI withdrawl feelings, i.e. the brain zaps. But I take only 50mg Effexor. Yes, really. Those symptoms disappear and are still gone now, some 7-8 hours later. I expected to feel an increase in the opiate withdrawl effects today, and that might have been the case a little in the morning, but this afternoon I had brief periods of feeling halfway okay bodily. I'm still weak as a kitten, prone to get too hot or cold easily, and it's also still hard to find a resting position that's comfortable for very long.
A few things are sure: I am most assuredly on less Tramadol now, much less, than I was a week ago. I am most assuredly much further into this attempt than I got into other attempts. I am most assuredly feeling much better during this attempt than I did during the other attempts. I am also taking way less Effexor than I expected to have to take to replace so much Tramadol.
One bad thing about the Effexor was that it made me intensely nauseous the first couple of days. Even a bowl of bland cold cereal in milk was difficult to put down. I fought that with Emetrol (OTC anti-nausea) with success. I still wanted to puke every now and then, but I was able to keep it in check with my mind. I had the Emetrol Monday, Tuesday, and Thursday, IIRC, and didn't have any today--and I actually felt spontaneously hungry for the first time today.
There has been a little diarrhea. Tuesday, day 2, was the worst for that. Took Immodium to control it that day, but have had none since. Stools have been very loose since then, but tolerable, so I tolerate.
I can tell my blood pressure is way down from what it was when I was on high doses of Tramadol. I can barely feel my heart in my own chest, which is a nice change I didn't know to expect.
I have had a total of 5 Tramadol in 5 days and I am now completely out. The script I have I can't refill for another 7 days from now. A shipment is on the way, but it's been "inbound into customs" for three days, and once it finally leaves there it'll be another two business days before it gets to me. I have no choice for the next 3 or 4 days at least to see what happens completely and totally without Tramadol.